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ISIS IOM product familyThe ISIS IOM product family offers 16 to 64 channel neuromonitoring systems in three flexible variants: a sturdy cart-based basic system, a high-end cart system with integrated printer and additional features and a portable laptop system.
ISIS IOM product familyISIS IOM product familyISIS IOM product family
ISIS IOM product familyThe ISIS IOM product family offers 16 to 64 channel neuromonitoring systems in three flexible variants: a sturdy cart-based basic system, a high-end cart system with integrated printer and additional features and a portable laptop system.


Variants
ISIS Xpert 32-channel system for neurosurgery
Item no.: 504005-32CHISIS Xpert 32-channel system for neurosurgeryThe powerful ISIS Xpert combines mobility with functionality. It consists of an equipment cart with panel PC, key­board drawer, accessory basket, constant-current stimulator, amplifier with a total of 32 recording channels (56 inputs: 8 referential and 48 differential) and all necessary adaptor boxes.
Available
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ISIS Xpert 16-channel system
Item no.: 504005-16CHISIS Xpert 16-channel systemThe powerful ISIS Xpert combines mobility with functionality. It consists of an equipment cart with panel PC, key­board drawer, accessory basket, constant current stimulator, amplifier with a total of 16 recording channels (24 inputs: 8 referential and 16 differential) and all necessary adaptor boxes.
Available
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ISIS Xpress 32-channel system for neurosurgery
Item no.: 504006-32CHISIS Xpress 32-channel system for neurosurgeryThe ISIS Xpress is the portable version of the ISIS IOM system. It consists of the ISIS Xpress base unit, trolley, notebook, notebook and accessory bag, constant current stimulator, amplifier with a total of 32 recording channels (56 inputs: 8 referential and 48 differential) and all necessary adaptor boxes.
Available
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ISIS Xpress 16-channel system
Item no.: 504006-16CHISIS Xpress 16-channel systemThe ISIS Xpress is the portable version of the ISIS IOM system. It consists of the ISIS Xpress base unit, trolley, notebook, notebook and accessory bag, constant current stimulator, amplifier with a total of 16 recording channels (24 inputs: 8 referential and 16 differential) and all necessary adaptor boxes.
Available
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Software modules
ISIS Software DataSync
Item no.: 504400ISIS Software DataSyncFor storing and accessing neuro­monitoring data from multiple ISIS systems via a central server
Available
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ISIS Software Screen2Video
Item no.: 504415ISIS Software Screen2VideoFor recording a desktop video of the NeuroExplorer application, e.g. for documentation and training purposes
Available
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ISIS Software Multi-channel Video
Item no.: 504418ISIS Software Multi-channel VideoFor displaying up to four video sources on the measurement screen, including recording function
Available
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ISIS Software Scalp-EEG
Item no.: 504423ISIS Software Scalp-EEGFor recording an electroencephalogram (EEG) as a raw signal and spectral analysis (CSA/DSA), for software version 8
Available
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ISIS Analysis Software
Item no.: 504401ISIS Analysis SoftwareFor viewing and analysing neuro­physio­logical measurements on a PC
Available
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ISIS Software EMG
Item no.: 504402ISIS Software EMGFor recording free-running and triggered elecromyography measurements (EMG)
Available
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ISIS Software Channel Select
Item no.: 504403ISIS Software Channel SelectFor selecting the best EMG signal when using the ALM Tube or Laryngeal Electrode Select
Available
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ISIS Software AEP
Item no.: 504404ISIS Software AEPFor recording auditory evoked potentials (AEP)
Available
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ISIS Software SEP
Item no.: 504406ISIS Software SEPFor recording somatosensory evoked potentials (SEP)
Available
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ISIS Software MEP
Item no.: 504408ISIS Software MEPFor recording motor evoked potentials (MEP)
Available
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ISIS Software Spine
Item no.: 504409ISIS Software SpineFor automated pedicle stimulation using triggered EMG
Available
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ISIS Software VEP
Item no.: 504410ISIS Software VEPFor recording visual evoked potentials (VEP)
Available
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ISIS Software EEG
Item no.: 504414ISIS Software EEGFor recording an electroencephalogram (EEG) or an electrocorticogram (ECoG), for software version 6 and 7
Available
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ISIS Software pIOM
Item no.: 504411ISIS Software pIOMFor performing pelvic intraoperative neuromonitoring by recording an EMG of the internal anal sphincter and measuring bladder pressure
Available
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ISIS Software TOF
Item no.: 504407ISIS Software TOFFor performing an automated train-of-four measurement for muscle relaxation measurement
Available
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ISIS Software ECoG
Item no.: 504424ISIS Software ECoGFor recording an electroencephalogram (EEG) or an electrocorticogram (ECoG)
Available
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Video interface for ISIS IOM incl. software and hardware
Item no.: 540013Video interface for ISIS IOM incl. software and hardwareConsisting of a video software license for NeuroExplorer software, Magewell USB Capture AIO, BNC interface
Available
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Extensions
ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEP
Item no.: 504285ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEP Enables the recording of 8 referential, 8 differential channels and the AEP stimulator. Can be combined with: 540340, 540523, 540525, 540531
Available
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ISIS Headbox 16 Ch. REF-AEP
Item no.: 504281ISIS Headbox 16 Ch. REF-AEPEnables the recording of 16 referential channels and the stimulation of AEPs. Can be combined with: 540522, 540524
Available
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ISIS Headbox 16 Ch. DIF
Item no.: 504271ISIS Headbox 16 Ch. DIFEnables the recording of 16 differential channels. Can be combined with: 520302, 540531, 540532, 540533, 540534, 540535
Available
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ISIS Headbox 16 Ch. REF
Item no.: 504261ISIS Headbox 16 Ch. REFEnables the recording of 16 referential channels. Can be combined with: 540524
Available
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ISIS Headbox U5S MER
Item no.: 590210ISIS Headbox U5S MEREnables the recording of 5 channels incl. test stimulation. Can be combined with: 590710, 590711
Available
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EP Adaptor for ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEP
Item no.: 540523EP Adaptor for ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEPFor maximal 8-channel recording to a common reference and the possibility to connect AEP Earphones (540340). Can be combined with: 504285, 540559
Available
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EP Adaptor for ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEP
Item no.: 540525EP Adaptor for ISIS Headbox 8 Ch. DIF-8 Ch. REF-AEPFor maximal 8-channel recording to a common reference. Can be combined with: 504285, 540559
Available
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EP Adaptor for ISIS Headbox 16 Ch. REF
Item no.: 540524EP Adaptor for ISIS Headbox 16 Ch. REFFor maximal 16-channel recording to a common reference. Can be combined with: 504281, 504261, 540560
Available
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EMG/MEP Adaptor Ch. 1-8 for 504271 for ISIS Headbox 16 Ch. DIF
Item no.: 540531EMG/MEP Adaptor Ch. 1-8 for 504271 for ISIS Headbox 16 Ch. DIFFor maximal 8-channel differential recording.
Available
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EMG/MEP Adaptor Ch. 9-16 for 504271 for ISIS Headbox 16 Ch. DIF
Item no.: 540532EMG/MEP Adaptor Ch. 9-16 for 504271 for ISIS Headbox 16 Ch. DIF For maximal 8-channel differential recording.
Available
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EMG/MEP Adaptor Ch. 1-8 for 504271 for colour-coded accessories
Item no.: 540533EMG/MEP Adaptor Ch. 1-8 for 504271 for colour-coded accessoriesFor maximal 8 colour-coded differential recording channels.
Available
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Stimulation Adaptor for ISIS Neurostimulator
Item no.: 540511Stimulation Adaptor for ISIS NeurostimulatorFor 8-channel high-current stimulation. Can be combined with: 504180
Available
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SEP Stimulation Adaptor for ISIS Neurostimulator
Item no.: 540501SEP Stimulation Adaptor for ISIS Neurostimulator4-channel high-current stimulation and 1-channel direct nerve stimulation (DNS). Can be combined with: 504180
Available
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Grid/TES Stimulation matrix 8 Ch. for ISIS Neurostimulator
Item no.: 540559Grid/TES Stimulation matrix 8 Ch. for ISIS NeurostimulatorFor interconnection of up to 8 electrode contacts for cortical stimulation and up to 6 electrodes for transcranial electrical stimulation using high-current stimulation, with LED illumination. Can be combined with: 540523, 540525, 540510, 504180
Available
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Grid/TES Stimulation matrix 16 Ch. for ISIS Neurostimulator
Item no.: 540560Grid/TES Stimulation matrix 16 Ch. for ISIS NeurostimulatorFor interconnection of up to 16 electrode contacts for cortical stimulation and up to 6 electrodes for transcranial electrical stimulation using high-current stimulation, with LED illumination. Can be combined with: 540522, 540524, 540510, 504180
Available
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MEP Stimulation Adaptor for Grid/TES Stimulation matrix
Item no.: 540510MEP Stimulation Adaptor for Grid/TES Stimulation matrixFor 8-channel high-current stimulation for connection to Grid/TES stimulation matrix. Can be combined with: 504180, 540559, 540560
Available
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pIOM Box for 504271/504285
Item no.: 520302pIOM Box for 504271/504285For connection to IONM devices
Available
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EP Adaptor for ISIS Headbox 16 Ch. REF-AEP
Item no.: 540522EP Adaptor for ISIS Headbox 16 Ch. REF-AEPFor maximal 16-channel recording to a common reference and the possibility to connect AEP Earphones (540340). Can be combined with: 504281, 504261, 540560
Available
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Accessories
Mute Sensor for suppression of HF noise
Item no.: 510025Mute Sensor for suppression of HF noiseFor use with C2 Xplore and ISIS IOM systems, delivered non-sterile, can be disinfected
Available
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AEP Insert Earphones for ISIS IOM systems and NeMo
Item no.: 540340AEP Insert Earphones for ISIS IOM systems and NeMoFor ISIS IOM systems with range of earplugs in three different sizes, silicon tubes red and blue, cable length 2 m, with Redel connector yellow, delivered non-sterile, not autoclavable
Available
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Foot switch to start a MEP stimulation
Item no.: 504136Foot switch to start a MEP stimulationFoot switch with USB connection, grey, non-sterile, wipe-disinfectable
Available
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LED flash goggles for VEP stimulation
Item no.: 505055LED flash goggles for VEP stimulation6 red LEDs, touchproof connection, R/L labelling, delivered non-sterile, wipe-disinfectable
Available
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Application accessories
Neurosurgery
NeurosurgeryFurther accessories for the application field

Available
Spine surgery
Spine surgeryFurther accessories for the application field

Available
Vascular surgery
Vascular surgeryFurther accessories for the application field

Available
Pelvic neuromonitoring
Pelvic neuromonitoringFurther accessories for the application field

Available
NeuroExplorer 8

All ISIS IOM systems are equipped with the new, particularly flexible NeuroExplorer software generation

Maximum flexibility for demanding neuromonitoring

Flexible configuration of measurement modalities (EMG, MEP, SEP, AEP, VEP, pIOM and ECoG) and the ability to combine a wide variety of applications mean you can individually tailor IONM to your clinical routine and research. The systems’ modular structure and the ability to individually combine different ISIS Headboxes and the ISIS Neurostimulator mean that the system can be individually configured for specific intraoperative neuromonitoring requirements and optionally also for microelectrode recording for deep brain stimulation.

At a glance

  • Up to 64 recording channels
    EMG, MEP, SEP, AEP, VEP, EEG, TOF, Spine (automated EMG), pIOM (bladder pressure and autonomous muscles)
  • 12-channel high-current stimulator (0.2–250 mA), 1-channel low-current stimulator (0.1–25 mA), anodal, cathodal, biphasic, alternating
  • Intuitive software with pre-installed scenarios and illustrated user manual
  • Patented stimulation artefact suppression
  • Dynamic mapping with visual and acoustic feedback
  • Multi-video window for up to four video sources and connection options to surgical microscopes and screens
  • Screen-to-video function for training and documentation
  • Display of measurement curves in Zeiss Kinevo miscroscopes
  • Multiple network integration options
  • Flexible data export and data streaming for backup and research
  • Professional training and support (courses, webinars, technical support)

Product features

Photo: ISIS Xpert plus with NEX8
NeuroExplorer 8
NeuroExplorer 8
NeuroExplorer 8
  • User-friendly design
  • Wide range of standard scenarios and templates – ideal for beginners
  • Flexible layout and many export options – perfect for experts
  • New possibilities with workflow scheduler, desktops and table view
  • Complete documentation thanks to the extended time bar and report function

Learn more NeuroExplorer 8
The intuitive NEX software offers a host of user-friendly functions, ensures clear overview and is quick to master in the often stressful operating room environment.
Photo: Headboxes of the ISIS IOM Systems
Modular structures for customised systems
Modular structures for customised systems
Modular structure
The ISIS IOM systems are characterised by their modular design, which enables you to configure them individually and tailor them to your specific requirements. In this way, you ensure that the systems are optimally customised to your needs. The number of channels can easily be expanded from 16 to 64 channels (ISIS Xpert and ISIS Xpert plus).
Thanks to the modular design of the ISIS IOM systems, they can be individually configured to your requirements.
Photo: Adaptor box with colour code
Easy to handle
Easy to handle
Easy to handle
Handling is simplified and made safer by colour-coded slots, plug connectors, cables, electrodes and measurement programmes. This colour code is also stored in the electrode scheme of the software and, together with the labelled adaptor boxes, enables fast electrode connection.
Easy and safe handling thanks to colour-coded slots, plug connections, cables, electrodes and measuring programmes.
Maximum interconnection and facilitated data transport
Maximum interconnection and facilitated data transport
Digital connectivity
With comprehensive HL7 support, we enable efficient communication and data exchange between different hospital information systems, medical devices and medical staff. Further integration possibilities, such as tablet use, printer connection or facilitated network integration, communicate wirelessly with each other. This leads to seamless and improved patient care, as the relevant data is made available in real time.
Possibility of full HL7 integration into the hospital network. Establishes the interface between the HIS and the IOM device.

Extension options

Each ISIS IOM system can be upgraded to up to 64 (ISIS Xpress 48) channels with additional amplifier and recording boxes (Headboxes). The following options are available:
 
Recording + AEP stimulation:  
ISIS Headbox 8Ch. DIF - 8Ch. REF - AEPItem no. 504285: 8 referential channels (e.g. VEP, EEG, SEP) + 8 differential channels (e.g. EMG, MEP)
ISIS Headbox 16Ch. REF - AEPItem no. 504281: 16 referential channels
 
Recording only: 
ISIS Headbox 16 Ch. DIFItem no. 504271: 16 differential channels
ISIS Headbox 16Ch. REFItem no. 504261: 16 referential channels
  
MER: 
ISIS Headbox U5S-MERItem no. 590210: 5 channels microelectrode recording

Relevant procedures

Relevant applications fields

Neurosurgery
Application Field
Neurosurgery
Neurosurgery deals with the detection and surgical treatment of diseases, malformations and injuries of the central and peripheral nervous system. Maintaining the nervous system’s functions during ...
Spine surgery
Application Field
Spine surgery
Spine surgery is a cross-disciplinary field that encompasses neurosurgical, orthopaedic and trauma surgery aspects. Ideally, all specialist disciplines work together to provide the best possible ...
Vascular surgery
Application Field
Vascular surgery
Vascular surgery is dedicated to the treatment of various diseases of blood vessels. Intraoperative neuromonitoring plays an important role in this application field, especially during surgery of ...
Pelvic intraoperative neuromonitoring
Application Field
Pelvic intraoperative neuromonitoring
Pelvic intraoperative neuromonitoring enables electrophysiological monitoring of nerve functions during surgical interventions in the small pelvis. pIOM® has been proven to improve functional ...
Thyroid surgery
Application Field
Thyroid surgery
The cutting-edge ALM (Advanced Laryngeal Monitoring) technology combines highly precise signal recording in thyroid surgery with intelligent software to provide a reliable nerve response signal. More ...
ENT surgery
Application Field
ENT surgery
Ear, nose and throat surgery includes many nerve-sparing procedures, which means that intraoperative neuro­moni­toring (IONM) plays an important role in protecting the facial nerve. IONM is ...
All applications fields of our products 

Which system is right for me?


Three different systems are available
ISIS XpertISIS Xpert plus and ISIS Xpress
ISIS XpertISIS Xpert plusISIS Xpress
ConfigurationISIS XpertISIS Xpert plusISIS Xpress
Sturdy cart with inbuilt systemxx-
Portable design with laptop and wheeled case with telescopic handle--x
Maximum number of channels646448
Number of accessory compartments12-
High-performance panel PCxx-
Touchscreenxx-
Ergonomic, height-adjustable monitor-x-
Printer+x+
Display external video sources on the measurement screen+x+
Integration with Zeiss Pentero® microscopes++-
External mute sensor to mute the loudspeaker in the event of disruptive artefacts from electrosurgery++-
Synchronisation of patient data over the network+++
Remote monitoring+++
Upgrade option to 5-channel MER+++
inomed planning software for DBS+++

xIncluded as standard

-Not available with this system

+Available as an additional option

Register now!

Enjoy a wide range of benefits

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